Practical aspects of proton homonuclear decoupling in solution NMR (Pure Shift)

This one-day workshop will start with a general presentation in the morning about the basic principles of homodecoupling: the principles of diverse approaches (Bandselective, Zangger-Sterk, BIRD, PSYCHE ; 1D and 2D experiments; real-time or pseudo-2D ; J-resolved experiments), discussing their advantages and drawbacks, and some practical applications.
Participants will subsequently be divided in two groups and follow two parallel sessions. During these sessions, the participants will have the opportunity to discuss specific cases of their own interest in an informal setting.
The first session will take place on the 900 MHz spectrometer and concerns the practical experimental setup of pure shift sequences.
In the second session, participants will be able to study concrete case-studies in silico and will be able to compare different pure shift experimental results.
Participants will follow each of these two sessions successively. Good basic Topspin operation skills are recommended.
Date : Monday 18th of November, 2019
Location: Campus CNRS de la Haute-Borne, Villeneuve d’Ascq. Speakers: Davy Sinnaeve, François-Xavier Cantrelle and Xavier Trivelli. Languages : English and French. Registration is free of charge, but only a maximum of 10 participants can be hosted.

Lieu : Campus CNRS de la Haute-Borne, Villeneuve d’Ascq, Intervenants : Davy Sinnaeve, François-Xavier Cantrelle et Xavier Trivelli, Langages : Anglais et Français, Inscriptions gratuites mais limitées à 10 places.

Registration (closed)*

* By registering for the practical training, you agree to register and participate in the meeting of the "users meeting" which will take place the next day

Workshop on Advanced NMR methods for quadrupolar Nuclei

This workshop will be dedicated to NMR characterization using advanced 1d/2D methods specific to quadrupolar nuclei. Studied topics will be :

  • Central Transition signal enhancement using population transfer (DFS/RAPT type experiments) ;

  • CPMG acquisition for enhancing signal ;

  • Correlation spectra between 1/2 and quadrupolar nuclei

    • D-HMQC 1H-{14N}

    • D-HMQC 27Al-{31P}

    • D-INEPT {27Al}-31P

  • Homonuclear correlation 2D spectra of quadrupolar spins (Double quantum 27Al spectra)

The workshop will start by a presentation of the different methods and the strategies to adopt as function of the investigated sample and nuclei, and will be followed a practical session on an 800 MHz spectrometer so that the participants can learn how these experiments can set-up.

To attend this workshop, a knowledge of the basics of NMR of quadrupolar nuclei (spin, energy levels, coherence, central and satellite transitions) is strongly recommended. It is particularly dedicated to people having a previous experience in 1D NMR of quadrupolar nuclei who would like to broaden their expertise by learning advanced methods for those isotopes.

Date: Monday 18th of November, 2019

Location: C4 building, "cité scientifique" campus, Lille University, Villeneuve d’Ascq, France

Speakers : Julien Trébosc, Olivier Lafon. Languages: English and French. Registration is free of charge, but only a maximum of 7 participants can be hosted.

Lieu : Campus CNRS de la Haute-Borne, Villeneuve d’Ascq, Intervenants : Davy Sinnaeve, François-Xavier Cantrelle et Xavier Trivelli, Langages : Anglais et Français, Inscriptions gratuites mais limitées à 10 places.

Registration *

* By registering for the practical training, you agree to register and participate in the meeting of the "users meeting" which will take place the next day